Linear 1 3-diarylpropanoids
Medchemexpress LLC Tetra(p-bromophenyl)porphyrin | 29162-73-0 | 95.0% | 930.32 | C44H26Br4N4 | 5 G
Tetra(p-bromophenyl)porphyrin is a brominated tetrakisphenylporphyrin used as a fluorescent dye and as a synthetic intermediate in porphyrin chemistry. It is employed as a porphyrin scaffold for derivatization and photophysical studies.
- Fluorescent tetrakisphenylporphyrin with four p-bromophenyl groups.
- CAS number 29162-73-0 and formula C44H26Br4N4.
- Molecular weight 930.32 g·mol-1.
- Light blue to blue solid, purity ~95.0%.
- Suitable as a building block for perfluoroalkyl-substituted porphyrins and other derivatives.
- Store protected from light and under inert atmosphere; cold storage recommended for solutions.
Medchemexpress LLC Dibenzoylmethane | 120-46-7 | 98.0% | 224.26 | 1 G
Dibenzoylmethane is a minor ingredient found in licorice that functions as a Keap1-Nrf2 activator. It is known to prevent various cancers and oxidative damage. As an analog of curcumin, it facilitates dissociation from Keap1, leading to the nuclear translocation of Nrf2.
- Activates Nrf2
- Prevents various cancers and oxidative damage
- Increases mRNA level of HO-1 in HepG2 cells
- Induces HO-1 and Nrf2 protein expression
- Increases phosphorylated protein levels of Erk1/2, p38MAPK, JNK, AMPK, and Akt in HepG2 cells
- Reduces area and severity of necrosis and leukocyte infiltration
- Protects against CCl4-induced liver damage
eMolecules 32864-38-3 | tert-Butyl ethyl propanedioate | ChemScene | MFCD00009193 | 188.223 | C9H16O4 | 95.000 | CCOC(=O)CC(=O)OC(C)(C)C | 25g | 791179218
tert-Butyl ethyl propanedioate | ChemScene | 32864-38-3 | MFCD00009193 | 188.223 | C9H16O4 | 95.000 | CCOC(=O)CC(=O)OC(C)(C)C | 25g | 791179218
Medchemexpress LLC L-Cysteine, L-γ-glutamyl-S-1-propen-1-yl- | 91216-96-5 | 99.3% | 290.34 | 25 MG
γ-Glutamyl-S-1-propenyl cysteine is a compound isolated from garlic.
- Appearance: Solid
- Color: White to off-white
- Initial source: Plants, Liliaceae, Allium sativum Linn.
- Shipping: Room temperature in continental US; may vary elsewhere
- Storage: -20°C, stored under nitrogen. In solvent: -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Medchemexpress LLC Trans-chalcone | 614-47-1 | MFCD00003082 | 98.8% | 208.26 g/mol | C15H12O | 500g
trans-Chalcone isolated from Aronia melanocarpa skin is a biphenolic core structure of flavonoids precursor trans-Chalcone is a potent fatty acid synthase (FAS) and -amylase inhibitor trans-Chalcone causes cellcycle arrest and induces apoptosis in the breastcancer cell line MCF-7 trans-Chalcone has antifungal and anticancer activity[1][2][3]
Medchemexpress LLC Trans-chalcone | 614-47-1 | MFCD00003082 | 98.8% | 208.26 g/mol | C15H12O | 5g
trans-Chalcone isolated from Aronia melanocarpa skin is a biphenolic core structure of flavonoids precursor trans-Chalcone is a potent fatty acid synthase (FAS) and -amylase inhibitor trans-Chalcone causes cellcycle arrest and induces apoptosis in the breastcancer cell line MCF-7 trans-Chalcone has antifungal and anticancer activity[1][2][3]
Medchemexpress LLC (E)-Naringenin chalcone | 25515-46-2 | 1 MG
(E)-Naringenin chalcone is an orally active anti-allergic agent that also possesses antioxidant and anti-inflammatory activities. It can improve adipocyte functions and inhibits histamine release from rat peritoneal mast cells. This product is for research use only.
- Orally active anti-allergic agent
- Possesses antioxidant activities
- Exhibits anti-inflammatory activities
- Improves adipocyte functions
- Inhibits histamine release from rat peritoneal mast cells
Medchemexpress LLC (S)-(+)-1,2-propanediol | 4254-15-3 | 99.97% | C3H8O2 | 10 MM 1 ML
(S)-(+)-1,2-Propanediol is an endogenous metabolite. It can be used as an organic solvent and diluent in drug preparations. It can also be used as a chiral synthetic intermediate and a substrate for enzyme research. It is for research use only.
- Endogenous metabolite
- Organic solvent and diluent in drug preparations
- Chiral synthetic intermediate
- Substrate for enzyme research
- For research use only
![Medchemexpress LLC 3-Pyridinecarboxamide, 6-[4-(1-aminocyclobutyl)phenyl]-5-pheny | 1357158-81-6 | 98.4% | 343.42 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000387556-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 3-Pyridinecarboxamide, 6-[4-(1-aminocyclobutyl)phenyl]-5-pheny | 1357158-81-6 | 98.4% | 343.42 | 1 ML
AKT-IN-1 is an allosteric AKT inhibitor with an IC50 of 1.042 μM. It potently inhibits phosphorylation of AKT in cells at both Thr308 and Ser473. In vivo, it causes significant tumor growth inhibition in breast adenocarcinoma xenograft models.
- Allosteric AKT inhibitor.
- Potently inhibits phosphorylation of AKT in cells at both Thr308 and Ser473, with IC50s of 0.422 and 0.322 μM respectively.
- Inhibits the phosphorylation of ribosomal protein S6, a downstream effector of the PI3K-AKT pathway.
- Potently inhibits the phosphorylation of PRAS40.
- In vivo, potently inhibits the phosphorylation of its downstream substrate GSK3β as well as the phosphorylation of AKT (Ser473).
- Causes significant tumor growth inhibition in BT474c breast adenocarcinoma xenograft models when dosed at 200 mg/kg daily.
Medchemexpress LLC Pinocembrin chalcone (2',4',6'-Trihydroxychalcone) | 4197-97-1 | 5 MG
Pinocembrin chalcone (2',4',6'-Trihydroxychalcone) is an antibacterial compound isolated from Helichrysum Trilineatum. It facilitates AMP-activated protein kinase (AMPK) activation, which improves glucose tolerance, increases muscle fatty acid oxidation (FAO), and reduces fat accumulation in the liver and skeletal muscles of high-fat diet-induced (HFD) diabetic mice. These properties make Pinocembrin chalcone a promising compound for research related to gastric ulcers and diabetes.
- Antibacterial activity: Inhibits the growth of S. aureus in vitro.
- Metabolic regulation: Significantly increases the fatty acid oxidation rate and enhances the phosphorylation of AMPKα in C2C12 myotubes.
- Anti-diabetic effects: Improves glucose tolerance and reduces fat accumulation in the liver and muscles in HFD-induced diabetic mice.
Medchemexpress LLC 4'-Methoxychalcone | 959-23-9 | 99.8% | 10 G
4'-Methoxychalcone regulates adipocyte differentiation through PPARγ activation. It also modulates the expression and secretion of various adipokines in adipose tissue that are involved in insulin sensitivity. This product is for research use only.
- Regulates adipocyte differentiation through PPARγ activation.
- Modulates the expression and secretion of various adipokines.
- Increases mRNA expression of adipogenic genes during differentiation.
- Reduces upregulated mRNA expression of inflammatory cytokines.
- Suitable for research use.
Medchemexpress LLC Brepocitinib P-Tosylate | 2140301-96-6 | 99.99% | 561.60 | 10 MG
Brepocitinib P-Tosylate is a potent dual Janus kinase 1 (JAK1) and TYK2 inhibitor with IC50s of 17 nM and 23 nM, respectively. It also inhibits JAK2 and JAK3 with IC50s of 77 nM and 6.49 μM, respectively. This product is intended for research use only.
- Potent dual JAK1 and TYK2 inhibitor
- Inhibits JAK2 and JAK3
- High purity of 99.99%
- Available in various quantities and forms
- Cited in multiple publications
- Undergoing various clinical trials
Medchemexpress LLC Isodecyl diphenyl phosphate | 29761-21-5 | MFCD00072254 | 99.0% | 390.45 | C22H31O4P | 10mg
Isodecyl diphenyl phosphate (IDPP) is a flame retardant IDPP has an ability to induce DNA damage and exertes S phase cell ratio-reducing effects in A549 cells[1]
Medchemexpress LLC Isodecyl diphenyl phosphate | 29761-21-5 | MFCD00072254 | 390.45 g/mol | C22H31O4P | 25mg
Isodecyl diphenyl phosphate (IDPP) is a flame retardant IDPP has an ability to induce DNA damage and exertes S phase cell ratio-reducing effects in A549 cells[1]